MEDLINE is the largest component of PubMed, the freely accessible online database of journal citations and abstracts created by the U.S. National Library of Medicine (NLM). Approximately 5,400 journals published in the United States and more than 80 other countries have been selected and are currently indexed for MEDLINE.
A distinctive feature of MEDLINE is that the records are indexed with NLM's controlled vocabulary, the Medical Subject Headings (MeSH).
A relatively small number of citations are available in PubMed and not MEDLINE.
Once you have formulated a search strategy you will need to select a resource (or resources) to search. To quickly find the answer, you would usually first search filtered (pre-appraised) resources, beginning at the top of the evidence hierarchy, moving lower down the hierarchy if required. If pre-appraised information is not available you will need to search unfiltered resources such as PubMed.
The EBP Toolkit aims to bring together all Evidence-Based online resources into a single entry point.
Resources are listed according to the hierarchy of evidence provided by the National Health and Medical Research Council (NHMRC):
Authors of critically-appraised topics evaluate and synthesise multiple research studies.
Authors of critically-appraised indivdual articles evaluate and synopsise individual research studies.
Evidence is not always available from filtered resources and searching primary literature is sometimes required. It is possible to use filters in PubMed and other databases to identify studies appropriate to the clinical question.